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Correlation Analysis

Microsoft Corp vs Vertex Pharmaceuticals Inc

MSFT vs VRTX

+0.770

Strong positive

When one moves up, the other tends to follow.

MSFT logo

Microsoft Corp

MSFT

Microsoft develops and licenses consumer and enterprise software. It is known for its Windows operating systems and Office productivity suite. The company is organized into three equally sized broad segments: productivity and business processes (legacy Microsoft Office, cloud-based Office 365, Exchange, SharePoint, Skype, LinkedIn, Dynamics), intelligence cloud (infrastructure- and platform-as-a-service offerings Azure, Windows Server OS, SQL Server), and more personal computing (Windows Client, Xbox, Bing search, display advertising, and Surface laptops, tablets, and desktops).

Market cap 2.8T

VRTX logo

Vertex Pharmaceuticals Inc

VRTX

Vertex Pharmaceuticals is a global biotechnology company that discovers and develops small-molecule drugs for the treatment of serious diseases. Its key drugs are Kalydeco, Orkambi, Symdeko, and Trikafta/Kaftrio, and Alyftrek for cystic fibrosis, where Vertex therapies remain the standard of care globally. Vertex has diversified its portfolio through Casgevy, a gene-editing therapy for beta thalassemia and sickle-cell disease, and Journavx, a non-opioid pain medication approved for the treatment of moderate-to-severe acute pain in adults. Additionally, Vertex is evaluating small-molecule inhibitors of APOL1-mediated kidney diseases. Vertex is also investigating cell therapies to deliver a potential functional cure for type 1 diabetes.

Market cap 110.5B · 6,400 employees

Apr 9, 2021 — Apr 7, 2026Daily1,254 observationsStockStockTechnologyHealthcare

Who Moves First

in sync

MSFT and VRTX tend to move at the same time.

Best correlation after shifting: +0.770 (13 shifts scanned)

Do They Crash Together?

Correlation by Market Regime

How these series behave when markets are rising, falling, or diverging. A correlation that holds in drawdowns is very different from one that only works in rallies.

Both Rising

-0.478

13 periods · Return correlation when both series rose

Both Falling

-0.265

6 periods · Return correlation when both series fell

Diverging

-0.508

16 periods · Return correlation when series moved apart

R-Squared

59.3%

Share of variance in one series explained by the other.

Trend Agreement

59.2%

How often both series moved in the same direction period-to-period.

Overlap Quality

1,254

Deep shared window — 1,254 usable pairs.

Significance

p < 0.001

95% CI: [0.746, 0.791]

Time Series

Rebased to 100

Green: MSFTGray: VRTX36 of 1,254 points (sampled)

Scatter

XY Regression

208.6250300350400450500549.3161.2200250300350400450500512.3Microsoft CorpVertex Pharmaceuticals IncData pointsFit (r = 0.77)

Pipeline

Data quality details

Pipeline Summary

1,254 paired observations survived the daily window.

Raw input

1,254

1,254

Normalized

1,254

1,254

Prepared

1,254

1,254

Aligned

1,254

1,254

Invalid removed

0

A: 0 / B: 0

Duplicates removed

0

A: 0 / B: 0

Alignment drops

0

A: 0 / B: 0

Series A

MSFT logo

Microsoft Corp

MSFT

Market cap 2.8T

Stock · 1,254 raw → 1,254 prepared

Series B

VRTX logo

Vertex Pharmaceuticals Inc

VRTX

Market cap 110.5B · 6,400 employees

Stock · 1,254 raw → 1,254 prepared

Sign agreement

100.0%

How often both values share the same sign.

Zero crossings

45

Estimated crossover points between normalized spreads.

Slope

0.9032

Linear regression slope.

Intercept

31.6539

Linear regression intercept.

Related Extremes

Highest and Lowest Correlated

Saved 3 hours ago · ID: stock-msft-vs-stock-vrtx-daily-20260408-471ubc