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Correlation Analysis

Microsoft Corp vs Biogen Inc. Common Stock

MSFT vs BIIB

-0.707

Strong inverse

When one moves up, the other tends to move down.

MSFT logo

Microsoft Corp

MSFT

Microsoft develops and licenses consumer and enterprise software. It is known for its Windows operating systems and Office productivity suite. The company is organized into three equally sized broad segments: productivity and business processes (legacy Microsoft Office, cloud-based Office 365, Exchange, SharePoint, Skype, LinkedIn, Dynamics), intelligence cloud (infrastructure- and platform-as-a-service offerings Azure, Windows Server OS, SQL Server), and more personal computing (Windows Client, Xbox, Bing search, display advertising, and Surface laptops, tablets, and desktops).

Market cap 2.8T

BIIB logo

Biogen Inc. Common Stock

BIIB

Biogen is an established biopharmaceutical company focused on treatments for neurodegenerative and rare diseases. Its declining multiple sclerosis franchise is its largest revenue generator and contributed 40% of total revenue in 2025. Biogen also generates significant revenue from its CD20 collaboration agreements with Roche (19% of total in 2025), which includes oncology drugs Rituxan and Gazyva and multiple sclerosis drug Ocrevus. Biogen's newer franchises include Spinraza (spinal muscular atrophy, with partner Ionis), Leqembi (Alzheimer's disease, collabroation revenue from its partner Eisai), Skyclarys (Friedreich's ataxia, Reata), Zurzuvae (postpartum depression, Sage), and Qalsody (amyotrophic lateral sclerosis, Ionis).

Market cap 25.3B · 7,500 employees

Apr 9, 2021 — Apr 7, 2026Daily1,253 observationsStockStockTechnology

Time Series

Rebased to 100

Green: MSFTGray: BIIB36 of 1,253 points (sampled)

Who Moves First

MSFT leads BIIB by 6 days

MSFT tends to move before BIIB.

Best correlation after shifting: -0.719 (13 shifts scanned)

Do They Crash Together?

Correlation by Market Regime

How these series behave when markets are rising, falling, or diverging. A correlation that holds in drawdowns is very different from one that only works in rallies.

Both Rising

+0.162

10 periods · Return correlation when both series rose

Both Falling

+0.191

8 periods · Return correlation when both series fell

Diverging

-0.604

17 periods · Return correlation when series moved apart

R-Squared

50.0%

Share of variance in one series explained by the other.

Trend Agreement

59.4%

How often both series moved in the same direction period-to-period.

Overlap Quality

1,253

Deep shared window — 1,253 usable pairs.

Significance

p < 0.001

95% CI: [-0.733, -0.678]

Scatter

XY Regression

212.7250300350400450500549102.6150200250300342.9Microsoft CorpBiogen Inc. Common StockData pointsFit (r = -0.707)

Pipeline

Data quality details

Pipeline Summary

1,253 paired observations survived the daily window.

Raw input

1,254

1,253

Normalized

1,254

1,253

Prepared

1,254

1,253

Aligned

1,253

1,253

Invalid removed

0

A: 0 / B: 0

Duplicates removed

0

A: 0 / B: 0

Alignment drops

1

A: 1 / B: 0

Series A

MSFT logo

Microsoft Corp

MSFT

Market cap 2.8T

Stock · 1,254 raw → 1,254 prepared

Series B

BIIB logo

Biogen Inc. Common Stock

BIIB

Market cap 25.3B · 7,500 employees

Stock · 1,253 raw → 1,253 prepared

Sign agreement

100.0%

How often both values share the same sign.

Zero crossings

5

Estimated crossover points between normalized spreads.

Slope

-0.5007

Linear regression slope.

Intercept

402.7199

Linear regression intercept.

Related Extremes

Highest and Lowest Correlated

Saved 3 hours ago · ID: stock-msft-vs-stock-biib-daily-20260408-6bmwvl