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Correlation Analysis

Biogen Inc. Common Stock vs BERKSHIRE HATHAWAY Class B

BIIB vs BRK.B

-0.802

Strong inverse

When one moves up, the other tends to move down.

BIIB logo

Biogen Inc. Common Stock

BIIB

Biogen is an established biopharmaceutical company focused on treatments for neurodegenerative and rare diseases. Its declining multiple sclerosis franchise is its largest revenue generator and contributed 40% of total revenue in 2025. Biogen also generates significant revenue from its CD20 collaboration agreements with Roche (19% of total in 2025), which includes oncology drugs Rituxan and Gazyva and multiple sclerosis drug Ocrevus. Biogen's newer franchises include Spinraza (spinal muscular atrophy, with partner Ionis), Leqembi (Alzheimer's disease, collabroation revenue from its partner Eisai), Skyclarys (Friedreich's ataxia, Reata), Zurzuvae (postpartum depression, Sage), and Qalsody (amyotrophic lateral sclerosis, Ionis).

Market cap 25.3B · 7,500 employees

BRK.B logo

BERKSHIRE HATHAWAY Class B

BRK.B

Berkshire Hathaway is a holding company with a wide array of subsidiaries engaged in diverse activities. The firm's core business segment is insurance, run primarily through Geico, Berkshire Hathaway Reinsurance Group, and Berkshire Hathaway Primary Group. Berkshire has used the excess cash thrown off from its operations to acquire Burlington Northern Santa Fe (railroad), Berkshire Hathaway Energy (utilities and energy distributors), and the companies that make up its manufacturing, service, and retailing operations (which include Precision Castparts, Lubrizol, Clayton Homes, Marmon, and IMC/ISCAR). The conglomerate is unique in that it is run on a completely decentralized basis. Berkshire is expected to generate close to $375 billion in revenue in 2025.

Market cap 1T

Apr 9, 2021 — Apr 7, 2026Daily1,253 data pointsStockStock

Time Series

Relative Performance

Green: BIIBGray: BRK.B36 of 1,253 points (sampled)

Who Moves First

BRK.B leads BIIB by 6 days

BRK.B tends to move before BIIB.

After testing 13 timing shifts, the strongest relationship was -0.808 (they moved in opposite directions).

Do They Crash Together?

Correlation by Market Regime

How these series behave when markets are rising, falling, or diverging. A correlation that holds in drawdowns is very different from one that only works in rallies.

Both Rising

+0.039

10 periods · Return correlation when both series rose

Both Falling

-0.523

8 periods · Return correlation when both series fell

Diverging

-0.605

17 periods · Return correlation when series moved apart

R-Squared

64.3%

Share of variance in one series explained by the other.

Trend Agreement

58.8%

How often both series moved in the same direction period-to-period.

Overlap Quality

1,253

Deep shared window — 1,253 usable pairs.

Significance

p < 0.001

95% CI: [-0.821, -0.781]

Scatter

XY Regression

102.6150200250300342.9247250300350400450500522.1Biogen Inc. Common StockBERKSHIRE HATHAWAY Class BData pointsFit (r = -0.802)

Pipeline

Data quality details

Pipeline Summary

1,253 paired data points survived the daily window.

Raw input

1,253

1,254

Normalized

1,253

1,254

Prepared

1,253

1,254

Aligned

1,253

1,253

Invalid removed

0

A: 0 / B: 0

Duplicates removed

0

A: 0 / B: 0

Alignment drops

1

A: 0 / B: 1

Series A

BIIB logo

Biogen Inc. Common Stock

BIIB

Market cap 25.3B · 7,500 employees

Stock · 1,253 raw → 1,253 prepared

Series B

BRK.B logo

BERKSHIRE HATHAWAY Class B

BRK.B

Market cap 1T

Stock · 1,254 raw → 1,254 prepared

Sign agreement

100.0%

How often both values share the same sign.

Zero crossings

3

Estimated crossover points between normalized spreads.

Slope

-1.1293

Linear regression slope.

Intercept

631.6559

Linear regression intercept.

Related Extremes

Highest and Lowest Correlated

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