Correlation Analysis
Alnylam Pharmaceuticals, Inc. vs Costco Wholesale Corp
ALNY vs COST
+0.706
Strong positive
When one moves up, the other tends to follow.
Alnylam Pharmaceuticals, Inc.
↗ALNY
Alnylam Pharmaceuticals is a leader in the study of RNA interference (RNAi) therapeutics. RNAi is a naturally occurring biological pathway within cells for sequence-specific silencing and regulation of gene expression. Alnylam's commercial RNAi therapeutic products include Onpattro and Amvuttra (for hATTR amyloidosis), Givlaari (for acute hepatic porphyria), and Oxlumo (for primary hyperoxaluria type 1), all developed and commercialized by Alnylam. Plus, Leqvio (for hypercholesterolemia) and Qfitlia (for hemophilia A or B), which are being commercialized by Alnylam's partners, Novartis and Sanofi, respectively. It also has several clinical programs across various therapeutic areas, including cardio-metabolic diseases, neuroscience, and hematology.
Market cap 43.8B · 2,500 employees
Costco Wholesale Corp
↗COST
Founded in 1983, Costco Wholesale now operates a global chain of membership-based warehouse clubs, delivering high-quality goods and services at consistently low prices. As of its most recent fiscal year, Costco operated approximately 910 warehouses, serving more than 80 million members across its three geographic segments: Costco US (approximately 73% of total revenue), Costco Canada (13%), and Costco International (14%).Costco's core value proposition—quality products at unbeatable prices—has yielded consistently strong member renewal rates (93% in the US and Canada and nearly 90% internationally). About 55% of Costco's fiscal 2025 revenue came from its grocery offerings, and another 25% from general merchandise.
Market cap 451.9B
Time Series
Relative Performance
Who Moves First
COST leads ALNY by 6 days
COST tends to move before ALNY.
After testing 13 timing shifts, the strongest relationship was +0.707 (they moved in the same direction).
Do They Crash Together?
Correlation by Market Regime
How these series behave when markets are rising, falling, or diverging. A correlation that holds in drawdowns is very different from one that only works in rallies.
Both Rising
-0.326
15 periods · Return correlation when both series rose
Both Falling
+0.583
9 periods · Return correlation when both series fell
Diverging
-0.774
11 periods · Return correlation when series moved apart
R-Squared
49.8%
Share of variance in one series explained by the other.
Trend Agreement
55.2%
How often both series moved in the same direction period-to-period.
Overlap Quality
1,253
Deep shared window — 1,253 usable pairs.
Significance
p < 0.001
95% CI: [0.677, 0.732]
Scatter
XY Regression
Pipeline
Data quality details
Pipeline
Data quality details
Pipeline Summary
1,253 paired data points survived the daily window.
Raw input
1,253
1,254
Normalized
1,253
1,254
Prepared
1,253
1,254
Aligned
1,253
1,253
Invalid removed
0
A: 0 / B: 0
Duplicates removed
0
A: 0 / B: 0
Alignment drops
1
A: 0 / B: 1
Series A
Alnylam Pharmaceuticals, Inc.
ALNY
Market cap 43.8B · 2,500 employees
Stock · 1,253 raw → 1,253 prepared
Series B
Costco Wholesale Corp
COST
Market cap 451.9B
Stock · 1,254 raw → 1,254 prepared
Sign agreement
100.0%
How often both values share the same sign.
Zero crossings
17
Estimated crossover points between normalized spreads.
Slope
1.7551
Linear regression slope.
Intercept
280.5519
Linear regression intercept.
Related Extremes
Highest and Lowest Correlated
ALNY
Alnylam Pharmaceuticals, Inc.
Highest
+0.842
JPMorgan Chase & Co.
JPM · 1,253 data points
Lowest
+0.460
Johnson & Johnson
JNJ · 1,253 data points
Saved 7 hours ago · ID: stock-alny-vs-stock-cost-daily